Semax

Russian short-course nootropic. Intranasal is the registered route.

What it does / how it works

An ACTH fragment with a Pro-Gly-Pro tail. Intranasal use is how it was registered in Russia. Animal work shows BDNF/trkB changes. Short courses, then off.

Class ACTH(4–10) analogue
Typical vial 5 or 10 mg
Reconstitution BAC or sterile water. Dilute to a practical nasal volume.
Storage after mix 2–8°C, use within 28 days

Protocol

Goal Dose How often How long Route
Days 1-14 200-600 mcg 1-2x daily 10-14 days Intranasal
Days 15-42 None Off 2-4 weeks off –
Repeat course Same 10-14 days Then off again Do not run 12 weeks straight Intranasal

Watch: Course peptide, not a 12-week weekly drug. Then 2–4 weeks off.

Semax FAQ — Australia

Base Peptides offers Semax in 10 mg vials, third-party tested at a leading Australian university. For research purposes only.
Both are Russian-developed nootropic peptides targeting different pathways. Semax is derived from ACTH(4-10) and primarily influences neurotrophic factors and cognitive performance. Selank is derived from tuftsin and primarily influences anxiolytic and immunomodulatory pathways. Some Australian research protocols use both compounds together.
Yes. Intranasal administration is well-documented in published Semax research and is the primary route used in Russian clinical studies. However, the lyophilised vial format from Australian suppliers is more commonly used with subcutaneous injection.
No. Despite being derived from ACTH fragment 4-10, Semax does not exhibit hormonal or steroidogenic activity. Published research has confirmed no significant effects on cortisol or other adrenal hormones in test subjects.
No. Despite being derived from ACTH fragment 4-10, Semax does not exhibit hormonal or steroidogenic activity. Published research has confirmed no significant effects on cortisol or other adrenal hormones in test subjects.

Recommended Supplier — Semax Australia

Our products offer premium-grade research materials with independent testing at a leading Australian university. Every batch is strictly verified by RP-HPLC and LC-MS. For research purposes only.

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