For research use only. Not for human consumption.
( 5.0 Ratings )
A targeted, mitochondria-penetrating peptide designed for research into mitochondrial dysfunction, cellular energy recovery, and the direct reduction of oxidative stress.
$119.85 $353.78Price range: $119.85 through $353.78
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SS-31 is a synthetic antioxidant peptide that belongs to the Szeto-Schiller (SS) family. It stands out in cellular biology because it ignores standard cell surface receptors and goes straight to the heart of cellular power generation: the mitochondria. It crosses cell membranes effortlessly due to its alternating structural design:
Binds Selectively to Cardiolipin: Once inside the cell, SS-31 targets and binds specifically to cardiolipin, a unique fat molecule found strictly within the inner mitochondrial membrane. Cardiolipin is essential for holding the electron transport chain (the cellular power generator) together.
Restores ATP (Cellular Energy) Production: When tissues suffer from aging, injury, or low oxygen, cardiolipin breaks down, causing the power generator to fall apart. By stabilizing cardiolipin, SS-31 patches the structural leaks, rapidly restoring normal adenosine triphosphate (ATP) energy production.
Inhibits Toxic Free Radical Production: Standard antioxidants try to clean up free radicals (reactive oxygen species, or ROS) after they have already leaked into the cell. SS-31 stops them at the source by optimizing electron flow, preventing toxic ROS from forming in the first place.
Prevents Programmed Cell Death: By protecting the inner membrane structure, it prevents the leakage of cytochrome c into the wider cell body. This prevents the cell from triggering premature apoptosis (programmed cell death) during metabolic stress.
| Property | Details |
| Product Name | SS-31 (Elamipretide / MTP-131) |
| Compound Type | Mitochondria-Targeted Antioxidant Peptide |
| Core Components | A small, basic tetrapeptide chain consisting of 4 alternating aromatic and cationic amino acids (D-Arg-Dmt-Lys-Phe-NH2). This configuration grants it an overall positive charge, drawing it naturally toward the negatively charged inner mitochondrial membrane. |
| Purity Standard | 98% or higher purity (verified by lab testing) |
| Appearance | Fine white powder (turns into a crystal-clear liquid when mixed) |
| pH Range | Formulated to sit between ~5.5–7.0 when reconstituted in standard sterile laboratory buffers |
| Storage (Unopened Powder) | Store in the freezer or fridge (-20°C to 4°C). Highly stable due to its compact peptide structure. Stable for 2–3 years. |
| Storage (Mixed Liquid) | Must be stored immediately in the fridge (2°C to 8°C). Do not freeze the liquid form, and protect it from prolonged exposure to direct ambient light. |
| Intended Use | Laboratory Research Only |
| Dosage | 10MG, 50MG |
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