For research use only. Not for human consumption.
( 5.0 Ratings )
A highly purified, long-acting GLP-1 receptor agonist designed for research into glucose-dependent insulin regulation, gastric motility, and neurological appetite pathways.
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Semaglutide operates as a long-acting glucagon-like peptide-1 (GLP-1) receptor agonist. It shares a 94% structural homology with native human GLP-1, modified specifically to resist enzymatic degradation by dipeptidyl peptidase-4 (DPP-4), thereby significantly extending its biological half-life in laboratory settings.
In research and clinical environments, the compound targets GLP-1 receptors across three primary therapeutic axes:
Pancreatic and Glycemic Regulation: Semaglutide binds to pancreatic beta-cells to stimulate glucose-dependent insulin secretion. Simultaneously, it suppresses alpha-cell glucagon secretion, lowering hepatic glucose output and preventing sharp postprandial glucose spikes.
Gastric Motility: The compound delays gastric emptying. By slowing down the rate at which nutrients are processed through the gastrointestinal tract, it modulates early digestion dynamics.
Neurological Appetite Control: Semaglutide crosses the blood-brain barrier to interact directly with the arcuate nucleus of the hypothalamus. It upregulates anorexigenic (satiety-inducing) pathways while downregulating orexigenic (hunger-stimulating) signaling, leading to a profound reduction in caloric demand and systemic appetite suppression.
| Property | Details |
| Product Name | Semaglutide |
| Compound Type | Synthetic Lipopeptide / GLP-1 Receptor Agonist |
| Core Components | A linear sequence of 31 amino acids modified with an Aib substitution at position 8, an Arg substitution at position 34, and a C-18 fatty acid di-acid chain acylated via a hydrophilic spacer to Lysine-26. |
| Purity Standard | ≥98.0% (Typically verified via High-Performance Liquid Chromatography / Mass Spectrometry) |
| Appearance | Lyophilized white to off-white solid cake/powder (reconstitutes into a clear, colorless solution) |
| pH Range | ~7.4 when reconstituted in sterile physiological buffers or bacteriostatic diluents |
| Storage (Unopened Lyophilized Solid) | Store at -20°C to 4°C (Stable for up to 24–36 months; must be protected from direct UV light and moisture) |
| Storage (Reconstituted Liquid) | Store at 2°C to 8°C (Refrigerated). Potency degrades rapidly if exposed to temperatures exceeding 30°C (86°F) or if subjected to mechanical freezing. |
| Intended Use | Laboratory Research Applications Only |
| Dosage | 10MG, 15MG, 20MG, 2MG, 30MG, 5MG |
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