What It Is
MK-677 (Ibutamoren) is an orally active, non-peptide growth hormone secretagogue (GHS) and selective ghrelin receptor agonist. It mimics the growth hormone-stimulating action of endogenous ghrelin by binding to growth hormone secretagogue receptors (GHSR) in the pituitary gland and hypothalamus.
What It Is Commonly Used For
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GH & IGF-1 Axis Upregulation: Studied for driving sustained, pulsatile elevations of endogenous growth hormone and Insulin-like Growth Factor 1 (IGF-1) without suppressing baseline pituitary function.
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Lean Mass & Bone Density Research: Evaluated in physiological models for promoting cellular nitrogen retention, muscle tissue synthesis, and bone mineral turnover.
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Appetite & Sleep Quality Signaling: Researched for its ability to stimulate central appetite pathways and optimize deep REM/slow-wave sleep architecture via GHSR activation.
General Purpose
To provide an oral non-peptide secretagogue for investigating growth hormone axis activation, IGF-1 synthesis, appetite regulation, and cellular tissue repair in laboratory research.
Specifications
| Property |
Details |
| Product Name |
MK-677 (Ibutamoren) |
| Product Category |
Growth Hormone Secretagogues & Selective Agonists |
| Compound Type |
Non-Peptide Ghrelin Receptor Agonist (Oral) |
| Primary Goal |
GH/IGF-1 elevation, nitrogen retention, and sleep architecture study |
| Form |
Oral liquid solution / capsules / tablets |
| Storage |
Store at room temperature (20°C to 25°C). Protect from moisture and direct light. |
| Intended Use |
Laboratory Research Only |