What It Is

Elorentide (commonly referred to as Eloralintide or development code LY3841136) is a novel long-acting synthetic amylin receptor agonist. It is engineered to selectively activate the calcitonin and amylin receptors in the central nervous system, mimicking the physiological effects of endogenous amylin to regulate appetite and metabolic homeostasis.

What It Is Commonly Used For

• Satiety & Appetite Modulation: Studied for its ability to delay gastric emptying and signal central satiety via brainstem pathways, leading to sustained food intake reduction.

• Metabolic & Body Composition Research: Evaluated in metabolic models for driving significant weight reduction and fat mass loss, particularly in combination with GLP-1 and GIP receptor agonists.

• Glycemic & Glucagon Regulation: Researched for its role in suppressing postprandial glucagon secretion and supporting balanced glucose clearance.

General Purpose

To provide a long-acting amylin receptor agonist for investigating central satiety pathways, gastric dynamics, and non-incretin metabolic regulation in laboratory research.

Specifications