MOTS-c

16-aa MDP. Mouse index paper is not a 5 mg human dose. 5 mg × 5 days/week is a research-vial convention.

What it does / how it works

A 16-amino-acid peptide encoded in mitochondrial DNA. In animal work it turns on AMPK and improves metabolic flexibility. Human vial schedules are convention, not the mouse mg/kg dose.

Class	Mitochondrial-derived peptide
Typical vial	10 / 20 / 40 mg
Reconstitution	1 mL BAC per 10 mg
Storage after mix	2–8°C, use within 28 days

Protocol

Goal	Dose	How often	How long	Route
Weeks 1-8 standard	5 mg	5 days on, 2 days off	4-8 weeks	SubQ
Conservative	5 mg	Mon / Wed / Fri	6-8 weeks	SubQ
Off	None	Stop	4 weeks off	–

Watch: A 10 mg vial is two 5 mg administrations.

MOTS-c FAQ — Australia

Where can I buy MOTS-c in Australia?

ELV8 Labs offers MOTS-c in 10 mg vials, third-party tested at a leading Australian university. For research purposes only.

Is MOTS-c really an exercise mimetic?

Published research has documented that MOTS-c activates similar metabolic pathways to physical exercise — particularly AMPK-mediated glucose uptake and fatty acid oxidation. However, it should not be considered a replacement for exercise in any context. The “exercise mimetic” label reflects specific metabolic pathway overlap, not equivalence.

How many vials of MOTS-c do I need for a protocol?

At 5 mg, 5 times weekly for 4 weeks, you need 10 vials (20 doses from 10 vials at 2 doses each). For 8 weeks at the same dose, you need 20 vials. Australian researchers should plan supply accordingly.

Can MOTS-c be combined with other peptides?

The age-related decline in circulating MOTS-c is attributed to declining mitochondrial function and reduced mitochondrial gene expression in aging cells. Published research has documented this decline in human subjects, contributing to the rationale for MOTS-c supplementation research in aged test subject models.

Why do MOTS-c levels decline with age?

Recommended Supplier — MOTS-c Australia

Our products offer premium-grade research materials with independent testing at a leading Australian university. Every batch is strictly verified by RP-HPLC and LC-MS. For research purposes only.

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