How Amino-1MQ Works

Amino-1MQ is a small-molecule inhibitor designed to target Nicotinamide N-methyltransferase (NNMT), an enzyme predominantly active in fat tissue (adipocytes) and liver cells. NNMT plays a major role in regulating cellular energy expenditure and NAD+ metabolism:

• NNMT Enzyme Inhibition: By selectively blocking NNMT activity, Amino-1MQ prevents the breakdown and methylation of nicotinamide (NAM), allowing the cell to conserve vital metabolic precursors.

• Accelerated Adipocyte Metabolism: In metabolic research models, blocking NNMT increases basal metabolic rate and cellular energy expenditure within fat tissue, promoting intracellular lipid oxidation without relying on central nervous system stimulants.

• Enhanced Skeletal Muscle Regeneration: Research shows that NNMT activity rises during muscle aging and damage. Inhibiting NNMT with Amino-1MQ enhances satellite cell proliferation, aiding in faster muscle fiber repair and resistance to muscle wasting.

Chemical Properties